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Key Takeaways
- Over-the-counter dandruff treatments can be used once or more a week to help fight dandruff. There are several different types of treatments with different active ingredients.
- Dandruff treatments can cause a dry or itchy scalp, and it may take a few tries to find the right treatment for your scalp.
- If you use a dandruff treatment for a month and don’t see improvement, or if your dandruff worsens, it may be time to see a dermatologist.
Over-the-counter dandruff treatments are shampoos used once or more per week (sometimes per day) to fight dandruff.
Ingredients that are effective at fighting dandruff and that you'll often find in dandruff shampoos include:
- Ciclopirox
- Coal tar
- Ketoconazole
- Salicylic acid
- Selenium sulfide
- Tea tree oil
- Zinc pyrithione (also sometimes called pyrithione zinc)
Read:
Questions to Ask a Dermatologist.
Here’s a little more background about some of the most common dandruff-fighting shampoo ingredients:
Ciclopirox is an ingredient used to treat seborrheic dermatitis, a chronic inflammatory skin condition that causes oily spots and scaly patches on the scalp. Seborrheic dermatitis also can cause recurrent dandruff.
Coal tar can be effective at fighting dandruff but it has a strong scent that may take some getting used to, says Dr. Anne Truitt, a board-certified dermatologist with Skin Surgery Medical Group in San Diego.
Ketoconazole is an antifungal. Plan to use it up to three times a week or as often as the label recommends. You may need to do more to moisturize your hair when using ketoconazole as it can be drying, says Dr. Steve Daveluy, an associate professor and program director of Wayne State University's Department of Dermatology in Detroit.
Although this active ingredient is effective, it can cause a yellow-brown discoloration on white, gray or dyed blonde hair. “Rinsing it out thoroughly can prevent this," Daveluy says.
Some dandruff shampoos use salicylic acid combined with another topical medication so the shampoo removes the flakes and the medication gets to the scalp.
Tea tree oil is an essential oil that can reduce the symptoms of dandruff and help stop the buildup of oil associated with dandruff.
Zinc pyrithione can be helpful for both dandruff and seborrheic dermatitis. If you choose this product, plan to use it three to four times a week and then a regular shampoo on other days you would wash your hair.
See:
Best Foods for Healthy Hair Growth
Use an OTC dandruff treatment just as you would any other shampoo for cleansing your hair. Here are a few tips to help you use an OTC dandruff shampoo effectively:
- Read the label to find out how often to use it. Some shampoos can be used daily if you wash your hair that often, while others are recommended for use only a couple of times a week. Too much use can dry the hair and cause the scalp to become dry and itchy.
- If you wash your hair daily but can use a dandruff shampoo only a couple times a week, use your regular shampoo on the remaining days. If you find that your dandruff shampoo dries out your hair, aim for a more gentle shampoo/conditioner on your off days.
- Aim to leave your dandruff shampoo on the scalp for five to 10 minutes before rinsing it out unless otherwise instructed. Consider turning off the shower water and doing another activity while letting the shampoo remain on the scalp.
- Be prepared for some trial and error to find the right dandruff shampoo for you. Anti-dandruff shampoos contain different ingredients, so you may respond to one ingredient better than another. Sometimes it may be effective to switch between two types of dandruff shampoos to get the best results from the ingredients.
Read:
Best Vitamins for Hair Growth
Each ingredient geared toward dandruff treatment may have potential side effects. Generally speaking, side effects of OTC dandruff treatment can include:
- Scalp dryness
- Skin irritation on the scalp
- An allergic reaction if you're allergic to an ingredient in the shampoo
Seek medical attention if you experience swelling, hives or trouble breathing after using an OTC dandruff treatment.
Here are some tips and precautions to keep in mind when using anti-dandruff shampoos.
- Avoid using a waxy hair conditioner or leave-in product. This can make dandruff worse.
- Keep your scalp protected from the sun. Some dandruff shampoos, such as those with coal tar, can make your scalp more sun-sensitive. The American Academy of Dermatology recommends using sun-protective clothing and wearing a wide-brimmed hat. You also can use a powder or spray sunscreen.
Dandruff occurs when the skin on your scalp scales or flakes off. Not only does it cause oiliness and itchiness, but it creates those annoying white flakes you may see on your clothes.
Dandruff is a common condition, affecting about 50% of the population, according to a 2023 report in the International Journal of Cosmetic Science.
Dandruff involves a yeast that lives on everyone’s skin, as well as sebum, a type of oil made by the body. Sebum on the scalp protects our hair, which is why dandruff can appear on the scalp. Skin then reacts to the yeast by causing flaking, itch and redness.
However, the exact cause of dandruff is unknown.
“We don’t know why some people dandruff and others don’t,” Daveluy says.
Dandruff can be more common in people with:
- Certain congenital conditions like Down syndrome
- Certain neurological issues, such as Parkinson’s disease or epilepsy
- Immunosuppression, including those with HIV infection
Although dandruff is definitely annoying, it’s not contagious. Usually, it can be treated without seeing a health care professional. However, dandruff also can be confused with:
- Allergic contact dermatitis, which is when you’re allergic to something that then touches your scalp. For instance, it could be an allergy to an ingredient in a hair product.
- Psoriasis, an autoimmune condition that can cause redness and flaking on the scalp.
- Ringworm of the scalp, a fungal infection that causes more severe redness, flaking and itch.
- Seborrheic dermatitis, a type of rash that scales and itches and also may appear on the face and chest. Dandruff is the mildest form of seborrheic dermatitis.
Since the signs of dandruff can be similar to the signs of other conditions, it's important to see a dermatologist if you try dandruff shampoos and they don't help.
If you'd like to try to get rid of your dandruff without using a dandruff shampoo, you can incorporate these ingredients into your hair care routine:
- Aloe vera. In addition to being great for sunburn relief, aloe vera can help reduce the inflammation and itchiness associated with dandruff. It can also keep your scalp moisturized.
- Apple cider vinegar. Apple cider vinegar is both an antifungal and a disinfectant, which has led to anecdotal reports of its effectiveness in fighting dandruff. Make sure to dilute it with water before applying it to your hair.
- Tea tree oil. The antifungal properties of tea tree shampoo can be helpful for dandruff. But never apply essential oils directly to your skin or scalp, as they can cause irritation. You'll want to dilute the oil first, and spot-test it in a small area to check for any potential reactions.
For most kids over the age of 2, it's OK to use a dandruff shampoo if needed. Read the instructions on the shampoo packaging, and ask a health care provider if you have any questions.
If you have a child under age 2 with dandruff, talk to a health care professional for guidance.
You should see a health care professional, like a dermatologist, if you are using an over-the-counter treatment for dandruff and it's not getting better after about a month or if it's getting worse.
“Dandruff is usually a lifelong condition,” says Dr. Sandy Marchese Johnson, a dermatologist with Johnson Dermatology in Fort Smith, Arkansas. “When you treat it, you should see results within one week on average. When you stop treatment, it often recurs within a week.”
“Dandruff and seborrheic dermatitis can often be frustrating, and working with a dermatologist can help decrease that frustration,” Johnson says.
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Methodology
The Best OTC Medicine & Health Products are based on the reviews of nearly 500 independent pharmacists and dermatologists.
U.S. News partnered with The Harris Poll, a global market research and consulting firm with more than 65 years of experience conducting surveys. For the 2025 rankings, The Harris Poll randomly assigned 133 over-the-counter categories of health or personal care products to 357 pharmacists and 134 dermatologists who practice in the U.S. and asked them to rank their top three brands for each category based on what products they would most recommend to consumers.
Independence and transparency
Across the 133 categories that were evaluated, each category included between five and 10 products representing their respective brands that could be ranked. More than 1,100 products were included in the survey. The products included in each category were selected to represent their respective brands based on input by several independent pharmacists and dermatologists on our
Medical Review Board. The list of products were finalized by the health editorial team to ensure all products can be purchased without a prescription and are readily available at most pharmacies or pharmacy sections of grocery stores in the U.S.
We independently evaluate the products we recommend. Brands do not pay to be included or ranked in our survey. When you buy through our links, we may earn a commission. The dermatologists and pharmacists who participated in the survey were paid a small honorarium by The Harris Poll for their time.
OTC category winners
Pharmacists and dermatologists selected their top three brands from representative products in each OTC category assigned to them. At least 112 dermatologists evaluated each skincare-related category and at least 108 pharmacists evaluated each of the other categories. For each evaluation, the top-ranked brand received 5 points, the second-place brand was awarded 3 points and the third-place brand earned 1 point. All unranked brands were given 0 points. Points were averaged for each brand. The results were then rescaled so the winner in each category scored 100 points, and the scores for other brands were expressed as percentages of the top score. Brands were then ranked according to their rescaled scores. Scores were rounded to the nearest whole number.
Category winners and brands that scored within the margin of error of the category winner and achieved a score of 80 or higher were given a Gold Badge in that category. The results: 196 brands received a Gold Badge. In total, 849 products are displayed. Brands that received a score of less than 10 were not included in the final display list. See our full methodology here.
Sources
The U.S. News Health team delivers accurate information about health, nutrition and fitness, as well as in-depth medical condition guides. All of our stories rely on multiple, independent sources and experts in the field, such as medical doctors and licensed nutritionists. To learn more about how we keep our content accurate and trustworthy, read oureditorial guidelines.
Steve Daveluy, MD, FAAD
Daveluy is an associate professor and director of the dermatology program at Wayne State University in Detroit.
Sandy Marchese Johnson, MD, FAAD
Marchese Johnson is a dermatologist with Johnson Dermatology in Fort Smith, Arkansas.
Anne Truitt, MD
Truitt is a board-certified dermatologist with Skin Surgery Medical Group in San Diego.